The Skyscan 1176 system is a live animal X-ray microtomography system which enables high-resolution 3D imaging of anaesthetised mice or rats using low X-ray doses.
The system is able to provide morphological detail of tissues including bone, muscle and fat while contrast agents can be used to produce 3D imaging of blood vessels, lymphatics and gastrointestinal spaces.
Variable X-ray applied voltages and filters provide scanning flexibility to allow imaging of a wide range of samples from lung tissue to bone with titanium implants as well as non-animal specimens. The instrument caters for full body mouse and rat scanning and for scanning of distal limbs of bigger animals such as rabbits.
An integrated physiological monitoring subsystem provides breathing and electrocardiogram gating to improve thoracic imaging.
Techniques
- X-ray micro computed tomography (Micro-CT)
Operating guides
- X-ray source 20-90kV
- Resolution 9, 18, 35 µm (pixel size)
- Maximum scan diameter 68mm
- Maximum scannable length of 200mm
- Minerve mice and rat imaging chambers with integrated anaesthesia and thermoregulation control
- Respiratory and electro cardiogram (ECG) gating for synchronised scanning
- Software for 2D and 3D image analysis, bone morphometry and volumetric modelling
Publishing data
Further information
Contacts
Location
CMCA rates
- Rates fall under standard CMCA access.
Animal Care
The Bioimaging Facility is committed to maintaining the highest standards of animal care and welfare. We operate in collaboration with Animal Care Services who provide pre and post imaging care.
All animal imaging procedures require approval from the UWA Animal Ethics Committee which incorporates a pre-submission discussion with both Animal Care Services and Bioimaging Facility staff.