The High Frequency Ultrasound has a wide range of protocols available to study blood flow, localization, and direction, tissue motion over time, presence of molecular biomarkers, anatomy and size of 2D, 3D and 4D regions and cardiac and vascular strain. Our high frequency ultrasound systems give you high resolution - down to 30 µm while imaging depths up to 3cm at frame rates up to 10,000 fps.

The Photoacoustic Imaging helps to study blood oxygen saturation and total haemoglobin, characteristics of nanoparticles, dyes and other contrast agents, drug delivery and pharmacokinetic analysis, micro distribution of biomarkers, cell tracking, and better understand complex disease mechanisms. Some of the advantages of this technology are real-time co-registration of molecular events with anatomy, high resolution oxygen saturation maps for hypoxia and ischemia and multi-target detection and quantification from one live scan! You can image in vivo tissue down to 2 cm in depth in real time and with a resolution down to 45 μm!


High Frequency Ultrasound Imaging

  • B-Mode
  • M-Mode
  • Anatomical M-Mode
  • Color Doppler Mode
  • Power Doppler Mode
  • Pulsed-Wave Doppler Mode
  • Tissue Doppler Mode
  • 3D-Mode
  • 4D-Mode
  • ECG and Respiration Gating
  • EKV (cardiac imaging)
  • Contrast Mode (Perfusion)
  • Digital RF-Mode

Photoacoustic Imaging

  • Oxy-hemo (oxygen saturation)
  • Single Wavelength
  • Multi-Wavelength
  • Spectro

Instrument Specifications

  • MX series of ultra-high frequency linear array transducers (10-71 MHz)
  • High-efficiency Vevo Optical Fibers come in 3 sizes and can be interchanged with the MX series transducers easily via their respective Vevo Fiber Jackets.
  • New laser technology for faster, more sensitive image acquisition at a wider wavelength range (680 - 970 nm and 1200 - 2000 nm). Comes with fully enclosed cabinet with interlocks
  • Vevo LAB analysis software with advanced tools for quantifying and characterizing indicators of disease progression and comes pre-packaged for applications in the following areas of research: oncology, cardiovascular, vascular, neurobiology and molecular imaging
  • Vevo Infusion pump available
  • Vevo Brain Stereotactic Frame available and comes with a High resolution ultrasound CD-1 mouse brain anatomical atlas
  • Hands-free scanning with Vevo Voice
  • Temperature controlled stage with active feedback
  • Anaesthetic vaporizer
  • Temperature, ECG, Respiratory, Blood pressure monitoring
  • ECG and respiratory gating

Further Information




CMCA rates

Animal Care

The NIF Bioimaging Facility is committed to maintaining the highest standards of animal care and welfare. We operate in collaboration with Animal Care Services who provide pre and post imaging care.

All animal imaging procedures require approval from the UWA Animal Ethics Committee which incorporates a pre-submission discussion with both Animal Care and Veterinary Services and Bioimaging Facility staff.